DESCRIPTION

ATZ 50 Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It is also used in the treatment of rheumatoid arthritis. ATZ 50 Tablet works by weakening the bodyÕs immune system, so it does not attack the new organ. The amount of medicine to be taken and how often you need to take it will depend on the type of transplant you have. Follow your doctorÕs instructions on this. You should take it along with food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ. It has many potential side effects. The most common are loss of appetite, nausea, and increased risk of bleeding. Because it suppresses your immune system, you may catch infections easily. ThereÕs also an increased risk of developing some cancers for this reason. You should ask your doctor about side effects that may need urgent medical attention. ATZ 50 Tablet can cause birth defects and miscarriages so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or if you have any unexpected bruising or bleeding. Your doctor also needs to know what other medicines you are taking as there are many which interact with this medicine and affect the way it works. You will have regular tests to check for any changes in the number of your blood cells.

INTRODUCTION

In Prevention of organ rejection in transplant patients ATZ 50 Tablet is an immunosuppressive agent that lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune system and help your body accept the new organ. In Treatment of Rheumatoid arthritis ATZ 50 Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

USE OF

Prevention of organ rejection in transplant patients | Treatment of Rheumatoid arthritis

BENEFITS

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ATZ 50 Tablet is to be taken with food.

FACTBOX 

Chemical Class::Nucleoside Analog, and Purines|Habit Forming::No|Therapeutic Class::ANTI NEOPLASTICS|Action Class::Immunosuppressant- Purine analogs

HOW TO USE

ATZ 50 Tablet is an immunosuppressant. It reduces the action of body’s own defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.

SAFETY ADVICE

– Alcohol : CONSULT YOUR DOCTOR – It is not known whether it is safe to consume alcohol with ATZ 50 Tablet. Please consult your doctor. – Pregnancy : CONSULT YOUR DOCTOR – ATZ 50 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. – Breast feeding : CONSULT YOUR DOCTOR – ATZ 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. – Driving : CONSULT YOUR DOCTOR – It is not known whether ATZ 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. – Kidney : CAUTION – ATZ 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of ATZ 50 Tablet may be needed. Please consult your doctor. Use of ATZ 50 Tablet is not recommended in patients with serious kidney disease. – Liver : CAUTION – ATZ 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of ATZ 50 Tablet may be needed. Please consult your doctor. Use of ATZ 50 Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while you are taking this medicine.

IF MISS

If you miss a dose of ATZ 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

COMMON SIDE EFFECT

Increased bleeding tendency | Nausea | Infection | Loss of appetite

ALCOHOL INTERACTION

CONSULT YOUR DOCTOR

PREGNANCY INTERACTION

CONSULT YOUR DOCTOR

LACTATION INTERACTION

CONSULT YOUR DOCTOR

KIDNEY INTERACTION

CAUTION

LIVER INTERACTION

CAUTION

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FAQ

Q. What is ATZ 50 Tablet prescribed for? How does it work?::: ATZ 50 Tablet is an immunosuppressant which means that it acts by suppressing the immune defense system of the body. Your immune defense system helps to protect you against infections. However, sometimes your immune defense system can become overactive and can cause illness. ATZ 50 Tablet is used in combination with other medicines to treat the conditions caused due to this abnormal activity of the immune system. It is used to prevent rejection of transplanted organs, like the kidney, heart or liver. It is also used to treat chronic active hepatitis, severe rheumatoid arthritis, systemic lupus erythematosus (SLE), idiopathic thrombocytopenic purpura and acquired hemolytic anemia. It is also used to treat severe cases of specified skin diseases (pemphigus vulgaris, dermatomyositis, polyarteritis nodosa, pyoderma gangrenosa), especially when corticosteroids cannot be used.| Q. How long does ATZ 50 Tablet take to start working?::: It may take about 3 to 12 weeks before you see any benefits. Continue the medication even if you do not notice any benefits. Talk to your doctor if you face any issues.| Q. What happens if I forget to take ATZ 50 Tablet?::: If you miss a dose of ATZ 50 Tablet, take it as soon as you remember. However, skip the missed dose if it is time for your next dose. Do not take a double dose to compensate for the missed dose. inform your doctor if the dose is frequently missed.| Q. How long do I need to take ATZ 50 Tablet?::: The duration varies from person to person as it is prescribed depending upon the patientÕs medical condition.| Q. Is breastfeeding safe during ATZ 50 Tablet treatment?::: No, breastfeeding should be avoided, while on ATZ 50 Tablet, since it may harm the baby and cause serious side effects.| Q. I have just started taking ATZ 50 Tablet. What are the long-term side effects? Is there anything I should be looking out for?::: Being an immunosuppressant, ATZ 50 Tablet can increase the chances of severe infections, decrease in blood cell counts, and malignancy. You should inform your doctor immediately if you notice any infection or fever, unexpected bruising or bleeding, black tarry stools or blood in the urine or stools. Let your doctor know if you notice any new skin sore or lump, new marks on skin or any change in the marks which were previously present.| Q. Do I need any special tests while I am on ATZ 50 Tablet?::: ATZ 50 Tablet reduces the production of blood cells making you more vulnerable to infections and can sometimes affect the liver. These side effects can be monitored by regular blood tests. Therefore, during the first 8 weeks of the treatment your doctor may recommend weekly blood tests to monitor complete blood counts, including platelet counts. The frequency can later be reduced to monthly or at least once in 3 months time.| Q. Can ATZ 50 Tablet cause cancer?::: ATZ 50 Tablet may increase the chance of developing certain cancers like skin cancer, cancer of the lymph system (lymphoma), cancer of soft tissues (sarcomas), and cervical cancer. To prevent the risk of skin cancer, avoid prolonged exposure to sunlight and wear protective clothing, sunglasses, and sunscreen. Tell your doctor immediately if you notice any changes in your skin or any lumps or masses anywhere on your body.| Q. Can cyclosporine and ATZ 50 Tablet be taken together?::: Yes, you can take cyclosporine and ATZ 50 Tablet together as they do not interfere with each otherÕs working. However, you must take the two medicines strictly as per your doctorÕs advice.

DISCLAIMER

The Contents of this website & medicine description are for informational purposes only and are not intended to be a substitute for professional medical advice, diagnosis, treatment, or prevention of a disease or medical condition. Please consult a physician or doctor for the treatment and/or management of any disease or medicalconditioin without delay.