Piroxicam (20mg)

DESCRIPTION

Prioxcan Tablet MD is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles. Prioxcan Tablet MD should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

INTRODUCTION

In Pain relief Prioxcan Tablet MD is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

USE OF

Pain relief

BENEFITS

Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow it. Prioxcan Tablet MD is to be taken with food.

FACTBOX 

Chemical Class::Enolic acid Derivatives|Habit Forming::No|Therapeutic Class::PAIN ANALGESICS|Action Class::NSAID’s- Non-Selective COX 1&2 Inhibitors (enolic acids)

HOW TO USE

Prioxcan Tablet MD is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

EXPIRY

Long shelf life (1-2 years).

SAFETY ADVICE

– Alcohol : UNSAFE – It is unsafe to consume alcohol with Prioxcan Tablet MD. – Pregnancy : CONSULT YOUR DOCTOR – Prioxcan Tablet MD is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. – Breast feeding : SAFE IF PRESCRIBED – Prioxcan Tablet MD is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. – Driving : UNSAFE – Prioxcan Tablet MD may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. – Kidney : CAUTION – Prioxcan Tablet MD should be used with caution in patients with severe kidney disease. Dose adjustment of Prioxcan Tablet MD may be needed. Please consult your doctor. No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine. – Liver : CAUTION – Prioxcan Tablet MD should be used with caution in patients with liver disease. Dose adjustment of Prioxcan Tablet MD may be needed. Please consult your doctor.

IF MISS

If you miss a dose of Prioxcan Tablet MD, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

COMMON SIDE EFFECT

Stomach pain | Nausea | Headache | Dizziness

ALCOHOL INTERACTION

UNSAFE

PREGNANCY INTERACTION

CONSULT YOUR DOCTOR

LACTATION INTERACTION

SAFE IF PRESCRIBED

KIDNEY INTERACTION

CAUTION

LIVER INTERACTION

CAUTION

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FAQ

Q. What is the difference between Prioxcan Tablet MD and diclofenac?::: Both Prioxcan Tablet MD and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase – an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Prioxcan Tablet MD.| Q. What is the difference between Prioxcan Tablet MD and naproxen?::: Both Prioxcan Tablet MD and naproxen are pain killers. Both are non-selective COX (cyclooxygenase – an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Prioxcan Tablet MD.| Q. What is the difference between Prioxcan Tablet MD and meloxicam?::: Both Prioxcan Tablet MD and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase – an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Prioxcan Tablet MD.| Q. What is the difference between Prioxcan Tablet MD and ketoprofen?::: Both Prioxcan Tablet MD and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Prioxcan Tablet MD. Ketoprofen gel also showed excellent tolerability.| Q. What is the difference between Prioxcan Tablet MD and tramadol?::: Prioxcan Tablet MD is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.| Q. What is the difference between Prioxcan Tablet MD and nimesulide?::: Both Prioxcan Tablet MD and nimesulide are pain killers. However, Prioxcan Tablet MD is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.| Q. Can Prioxcan Tablet MD be used in the treatment of chikungunya?::: Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Prioxcan Tablet MD or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Prioxcan Tablet MD.| Q. Are Prioxcan Tablet MD and aspirin same?::: No. Prioxcan Tablet MD and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.| Q. Can Prioxcan Tablet MD be used along with dexamethasone?::: No. Prioxcan Tablet MD should not be used with dexamethasone. They both increase each other’s toxicity. There is an increased risk of GI ulceration.| Q. Can Prioxcan Tablet MD be used with methocarbamol?::: Yes. Methocarbamol can be used with Prioxcan Tablet MD as no serious side effects are known. Inform your doctor before starting any of the medication.| Q. Can Prioxcan Tablet MD be used along with paracetamol?::: Yes. Paracetamol can be used with Prioxcan Tablet MD as no serious side effects are known. Inform your doctor before starting any of the medication.| Q. Is Prioxcan Tablet MD a NSAID?::: Yes. Prioxcan Tablet MD is a non-steroidal anti-inflammatory drug (NSAID).| Q. Is Prioxcan Tablet MD a sulfa drug?::: Prioxcan Tablet MD is a sulphur containing compound. Prioxcan Tablet MD can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.| Q. Is Prioxcan Tablet MD a blood thinner?::: No. Prioxcan Tablet MD is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder. | Q. Is Prioxcan Tablet MD a muscle relaxant?::: No. Prioxcan Tablet MD is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.| Q. Is Prioxcan Tablet MD a narcotic?::: No. Prioxcan Tablet MD is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.| Q. Can Prioxcan Tablet MD be used in hypertension?::: No. Prioxcan Tablet MD is not a medication to control hypertension. It is important to note that Prioxcan Tablet MD decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Prioxcan Tablet MD.| Q. Can Prioxcan Tablet MD be used along with Losartan?::: No. Prioxcan Tablet MD should not be combined with Losartan. It is important to note that Prioxcan Tablet MD decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Prioxcan Tablet MD.| Q. Can Prioxcan Tablet MD be used with Lisinopril?::: No. Prioxcan Tablet MD should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Prioxcan Tablet MD.| Q. Can Prioxcan Tablet MD be used with calcium channel blocker?::: Yes. Prioxcan Tablet MD can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)| Q. Can Prioxcan Tablet MD be used with Tizanidine?::: Yes, Prioxcan Tablet MD can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.| Q. Why is beta cyclodextrin added to Prioxcan Tablet MD?::: Yes. Prioxcan Tablet MD can be combined with beta-cyclodextrin. Research has shown that combining Prioxcan Tablet MD with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.| Q. Are there any alternatives of Prioxcan Tablet MD?::: Yes. There are alternatives to Prioxcan Tablet MD. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.| Q. What are the contraindications for Prioxcan Tablet MD?::: Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.| Q. Can Prioxcan Tablet MD be used in the treatment of allergy?::: No. Prioxcan Tablet MD is not a drug to treat allergy. It is a pain killer.| Q. How long does Prioxcan Tablet MD work?::: Prioxcan Tablet MD is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.| Q. Can you get high by using Prioxcan Tablet MD?::: No. Prioxcan Tablet MD is not known to cause high. It is a non-narcotic painkiller.| Q. Can Prioxcan Tablet MD be used to treat menstrual cramp?::: Prioxcan Tablet MD is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.| Q. Can I use Prioxcan Tablet MD for a migraine?::: Prioxcan Tablet MD is not approved for the treatment of migraine. Research studies have shown that Prioxcan Tablet MD is effective in significantly decreasing the pain associated with migraine without aura.| Q. Is Prioxcan Tablet MD effective in back pain management?::: Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Prioxcan Tablet MD as the cause of back pain can be different for different person.| Q. Is Prioxcan Tablet MD affective in gout management?::: Yes. Prioxcan Tablet MD can be given for the treatment of acute gout. Research studies have shown Prioxcan Tablet MD to be highly effective in the treatment of acute gout.| Q. Can you donate blood when on the medication with Prioxcan Tablet MD?::: Yes. You can donate blood when on Prioxcan Tablet MD. Do inform your doctor before donating blood.| Q. Can I use Prioxcan Tablet MD if I am a diabetic?::: Prioxcan Tablet MD in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Prioxcan Tablet MD so taking piroxicam can lead to increased risk of renal failure by many folds.| Q. Can I use Prioxcan Tablet MD if I have a deranged renal function?::: No. Prioxcan Tablet MD should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.| Q. Can Prioxcan Tablet MD lead to skin reactions?::: Yes. Prioxcan Tablet MD is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.| Q. Can I use Prioxcan Tablet MD if I am pregnant?::: No. Prioxcan Tablet MD should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.| Q. Can I use Prioxcan Tablet MD if I have peptic ulcer disease?::: No. Prioxcan Tablet MD is contraindicated in cases of active peptic ulcer disease. Prioxcan Tablet MD is known to cause gastric ulceration and bleeding.| Q. Can I use Prioxcan Tablet MD if I have asthma?::: Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.| Q. Can Prioxcan Tablet MD lead to difficulty in conception?::: Yes. Prioxcan Tablet MD can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.| Q. Can Prioxcan Tablet MD be used with diuretics?::: No. Prioxcan Tablet MD should not be used with diuretics. Prioxcan Tablet MD reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.| Q. Can Prioxcan Tablet MD be used with lithium?::: No. Prioxcan Tablet MD should not be used with lithium. Prioxcan Tablet MD leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.| Q. Can Prioxcan Tablet MD be used with warfarin?::: No. Prioxcan Tablet MD should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.| Q. What increases the chances of getting a gastric ulcer when I am already taking Prioxcan Tablet MD?::: The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.| Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Prioxcan Tablet MD?::: Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.| Q. What are the serious side effects of Prioxcan Tablet MD?::: GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

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